After the Kefauver Harris Amendment was passed in 1962, the . FDA began the DESI review process to ensure the safety and efficacy of drugs approved under the more lenient pre-1962 standards, including Dianabol.  In 1965, the FDA pressured CIBA to further document its legitimate medical uses, and re-approved the drug for treating post-menopausal osteoporosis and pituitary-deficient dwarfism .  After CIBA's patent exclusivity period lapsed, other manufacturers began to market generic metandienone in the .
Recent trials with beef-producing heifers have mostly been based on the use of an androgen, although oestrogens have been tested, alone or in combination. Thus, zeranol has been reported to increase gain (62, 63), while in other trials no response has been observed (37, 62). TBA administered alone (300 mg) has led to increases in weight gain and FCE of the order of 36% and 25% respectively (24, 27, 37, 64, 65, 66, 67, 68, 69, 70). In other trials, combinations of an oestrogen with TBA (68) or testosterone (62) have yielded significant growth responses. In general, it appears that the effect of TBA alone in heifers corresponds closely to the effect of combined oestrogen/TBA implants in steers.
Anabolic steroid implants are allowed for veterinary use. But if someone diverts this for use in humans, it will be deemed as a distribution of a Schedule III drug leading to prosecution. The law on trenbolone differs in other countries. For instance, in Canada it is a Schedule IV drug. In Canada, all anabolic steroids are classified as Schedule IV drugs. In the UK, anabolic steroids are classified as Class C substances. Their possession can lead to a 2 year jail term, while their production and supply can lead to a 14 year jail term. But many countries do not have strict laws. In some places, you can even buy it over the counter.