Side effects of using topical corticosteroids

Omeprazole acts as an inhibitor of CYP2C19. Omeprazole, given in doses of 40 mg daily for one week to 20 healthy subjects in cross-over study, increased Cmax and AUC of cilostazol by 18% and 26% respectively. C max and AUC of one of its active metabolites, 3,4-dihydro-cilostazol, which has 4-7 times the activity of cilostazol, were increased by 29% and 69% respectively. Co-administration of cilostazol with omeprazole is expected to increase concentrations of cilostazol and its above mentioned active metabolite. Therefore a dose reduction of cilostazol from 100 mg twice daily to 50 mg twice daily should be considered.

Physicians should advise patients to stop use of all PDE5 inhibitors, including VIAGRA, and seek medical attention in the event of a sudden loss of vision in one or both eyes. Such an event may be a sign of non-arteritic anterior ischemic optic neuropathy (NAION), a cause of decreased vision including possible permanent loss of vision, that has been reported rarely post-marketing in temporal association with the use of all PDE5 inhibitors. It is not possible to determine whether these events are related directly to the use of PDE5 inhibitors or to other factors. Physicians should discuss with patients the increased risk of NAION in individuals who have already experienced NAION in one eye. Physicians should also discuss with patients the increased risk of NAION among the general population in patients with a “crowded” optic disc, although evidence is insufficient to support screening of prospective users of PDE5 inhibitor, including VIAGRA, for this uncommon condition [see WARNINGS AND PRECAUTIONS and ADVERSE REACTIONS ].

Thanks so much for the information on Splenda. I have been a heavy user of Splenda (Coffee, on my Oatmeal, other foods that are enhanced with “sugar”, etc.) I have never had problems with dryness of the mouth or significantly chapped lips. Even when I was in the Korean War and slept in foxholes outside where the temperature at times was 20 to 30 degrees below zero, I did not suffer from chapped lips or dryness of the mouth. Lately however, I have encountered a significant dryness of my lips (to the point of splitting and bleeding)and dryness in the front inside of my mouth. Reacting normally to the dry lips, I have tried practically every lip balm on the market; however, while I have enjoyed temporary relief at times, the dryness has returned like clock work. I have been trying to isolate foods/drinks/alcohol/etc. in my diet in an attempt to pinpoint what might be causing this dryness. I have not been able to identify what has been causing my problem. Now, after reading about Splenda (Sucralose) and reading the testimonies of others, I on this day am removing all Splenda from my diet because it is very possible that with my heavy use of Splenda, I have ingested a significant amount of chlorine. I will monitor any changes in the dryness of my mouth and the chapness of my lips and let you know if there have been any relief. Thanks so much for the information on Splenda.

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Side effects of using topical corticosteroids

side effects of using topical corticosteroids

Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.

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