Studies with oral and intravenous dosing of radiolabeled ciclesonide have shown an incomplete extent of oral absorption (%). The oral bioavailability of both ciclesonide and the active metabolite is negligible (<% for ciclesonide, <1% for the metabolite). Based on a γ-scintigraphy experiment, lung deposition in healthy subjects is 52%. In line with this figure, the systemic bioavailability for the active metabolite is >50% by using the ciclesonide metered dose inhaler. As the oral bioavailability for the active metabolite is <1%, the swallowed portion of the inhaled ciclesonide does not contribute to systemic absorption.
Thanks a lot. I am really inspired with your efforts to remove quite a lots of misconceptions about Homeopathy in general public. Many Leading Homeo drs are least interested in educating people about this. Many times i have asked my doctor ( one of the leading homeo dr in my city) and he says that it is out of jealousy people are spreading this propaganda. But my question is what is your effort in preventing this spread of false propaganda. Anyway i am really happy that, though you are always a busy person, but when approached- very mild, scientific tempered and matured person. May god give you more and more strength to spread homeopathy in a scientific spirit.