Research studies focused on inhaled steroids found that there was an increased risk of cataract with higher dosages of the steroid. They also found that there was little to no increased risk in patients that took the lowest daily steroid dose, about 500 mcg (micrograms). But they found that the risk increased to 70% for those taking the highest dose, up to 1600 mcg. The risk also increased the longer a person took an inhaled steroid. Risk for developing those type of cataracts also increased if among older patients. Changes that occur to the lens of the eye that make us susceptible to develop normal “older-age” types of cataracts also make us more susceptible to developing posterior subcapsular cataracts when taking higher doses of steroids.
In an embryofetal development study in pregnant rabbits, beclomethasone dipropionate administration during organogenesis from gestation days 7 to 16 at subcutaneous doses equal to and greater than times the MRHDID in adults (on a mg/m 2 basis at maternal doses of mg/kg/day and higher) produced external and skeletal malformations and embryolethal effects (increased fetal resorptions). There were no effects in fetuses of pregnant rabbits administered a subcutaneous dose times the MRHDID in adults (on a mg/m 2 basis at a maternal dose of mg/kg/day).
It does state that your Doctor will monitor your health on taking this drug. I have only been on this dose for three weeks and the lower dose for about a month. Last year I was on seretide 250 for 3 months January - March/April and wasn't aware of any other side effects than thrush which is easy treated. I am now back on Seretide at 250 dose. I going to see my asthma nurse shortly for a review. I have gain weight in the last three weeks but I can't blame the medication as I not been able to go swimming 3 times a week (like I normally do) this couple with the 20 min walk there and back usually keeps me fit and keeps me weight down.