Brassinosteroid production and signaling differentially

There is also a study of the brassinosteroid, 28-Homobrassinolide (HB), in rats which can also be used as a proxy for Laxogenin. The study concluded that HB stimulated protein synthesis and inhibited protein degradation in part by inducing Akt phosphorylation . [9] Akt is a serine/threonine kinase that signals downstream of growth factor receptors and phosphoinositide-3 kinase PI3K. Akt also stimulates glucose uptake, glycogen synthesis via Akt/mTOR and Akt/GSK-3β signaling networks. [10] In addition, HB triggered a selective anabolic response with minimal to no androgenic side-effects. [9]

As we all know, your hormones play a crucial role in your ability to build muscle, burn fat, and generally live a healthy, happy life. Laxogenin encourages an optimal muscle-building environment by regulating cortisol levels in the body. Excessive cortisol levels are the archenemy of muscle growth. It’s incredibly catabolic and can significantly impair your ability to build muscle protein and it may even lead to atrophy -- muscle wasting![7] While you do need some cortisol to function properly, too much can severely hamper your efforts to build slabs of lean muscle.

Research:  I am broadly interested in investigating novel strategies and refining existing restoration techniques that improve ecological sequestration of greenhouse gases in working landscapes and wild lands without significantly compromising on traditional restoration goals such as protecting biodiversity and safeguarding ecosystem services.  I would like to develop strategies of minimal intervention and disturbance that reduce the use of heavy machinery, herbicides, and chemical inputs to control cost and that are feasible in highly restricted or rugged areas such as designated Wilderness.  I hope to orient my research towards informing concrete policies and advocating for interagency and private-public coordinated action to protect the lands we depend on for our survival, quality of life, economy, and systems for these goals include grazed lands dominated by invasive annual grasses in California’s lower elevations and forest systems impacted by severe fire in the Sierra Nevada and California Coast ranges.

Brassinosteroid production and signaling differentially

brassinosteroid production and signaling differentially

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